Integrated scale down of the primary downstream purification process and assessment of alternative process options for the production of an ovine polyclonal antibody based anti-venom

This thesis describes the development of a linked 1000th scale mimic of four distinct unit operations, including precipitation and centrifugation. These operations are utilised during the production of an anti-snake venom Fab fragment. A new approach has been used to define the important engineering...

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Bibliographic Details
Main Author: Neal, G. E.
Published: University College London (University of London) 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.639479