Regulation of hepatic stellate cell phenotype and cytoglobin expression by extracellular matrix proteins

All chronic liver diseases can induce fibrosis and lead to liver cirrhosis. Within liver disease, hepatic stellate cells (HSC) are accepted as the major effectors of fibrogenesis and changes in the extracellular matrix (ECM). Cytoglobin (CYGB), a hexacoordinated globin, is upregulated in liver disea...

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Bibliographic Details
Main Author: Stone, Louise Catherine
Published: University of Birmingham 2015
Subjects:
500
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.636854