DNA damage response and anti-apoptotic proteins expression in NPMc+ mutated cells in acute myeloid leukaemia

Nucleophosmin 1 (NPM1) is a multi-functional phosphoprotein, which shuttles between the nucleolus and the cytoplasm. It participates in many cellular processes including ribosome biogenesis and transport, centrosome duplication, and also contributes to the control of genomic stability. NPM1 interact...

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Bibliographic Details
Main Author: Qutob, Haitham
Published: University of Nottingham 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.635075