Thermostable DNA polymerases in replication, repair and biotechnology

Many archaea contain a unique DNA polymerase, DNA Pol D. This enzyme is a heterodimer composed of a large subunit (polymerase) and a small subunit (3’- 5’ proof reading exonuclease). The enzyme from Pyroccocus furiosus is inhibited by the presence of uracil in template strands. This research has sho...

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Bibliographic Details
Main Author: Gilroy, Louise
Published: University of Newcastle upon Tyne 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.635036