Cryo-electron microscopy of Weibel-Palade Bodies in human endothelial cells

Weibel-Palade bodies (WPBs) are a secretory storage organelle found in endothelial cells. Their primary cargo is the large haemostatic protein von Willebrand factor (VWF), however there are many other minor components, both in the membrane and lumen of the WPB. VWF is stored in long helical tubules...

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Bibliographic Details
Main Author: Streetley, J. W. A.
Published: University College London (University of London) 2014
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634718