The immunomodulatory effects of vitamin D on mononuclear phagocytes
Expression of the vitamin D receptor on mononuclear phagocytes renders them susceptible to modulation by 1,25(OH)2D3, which is metabolised from its precursor 25(OH)D3 by the enzyme CYP27B1. Modulation of dendritic cells (DC) with 1,25(OH)2D3 has been shown in vitro to suppress their ability to prime...
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University College London (University of London)
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634690 |