The role of the folate and methylation cycles in neural tube closure

Neural tube defects (NTD) are congenital malformations caused by abnormalities in the developmental process of neurulation. Folate metabolism appears to be a determinant of risk of NTD since periconceptional supplementation with folic acid has been shown to reduce the frequency of NTD in humans whil...

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Bibliographic Details
Main Author: Dunlevy, L. P. E.
Published: University College London (University of London) 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634568