Investigating the role of phosphorylation in the regulation of Diacylglycerol Lipase α/β activity

Diacylglycerol Lipase α (DAGLα) and β (DAGLβ) hydrolyse diacylglycerol (DAG) to produce 2-arachidonoylglycerol (2-AG), the main endogenous ligand for the cannabinoid receptors 1 (CB1) and 2 (CB2). Anatomical and pharmacological studies, complimented by knockout models, of these enzymes have implicat...

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Bibliographic Details
Main Author: Singh, Praveen
Published: King's College London (University of London) 2013
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634125