Forward genetic analysis of natural T regulatory cell development

Natural (n) T regulatory (Treg) cells generated in the thymus are essential throughout life for the maintenance of T cell homeostasis and prevention of autoimmunity. T cell receptor (TCR)/CD28-mediated activation of Nuclear Factor Kappa-light-chain-enhancer of activated B cells (NFB) and Jun N-term...

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Bibliographic Details
Main Author: Salisbury, Emma
Other Authors: Ashton-Rickardt, Philip : Pusey, Charles
Published: Imperial College London 2013
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.634085