Exploring the role of the molecular chaperone Hsp104 in yeast [PSI+] prion propagation and transmission
[PSI+] is the prion form of the Sup35 protein in Saccharomyces cerevisiae. The molecular Hsp 104 chaperone is involved in the propagation of the [PSI+] by dissolving Sup35p prion fibres into the small seeds (propagons) needed to generate a new round propagation. Overexpression of the HSP104 gene res...
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University of Kent
2013
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.633824 |