The role of SOX2 in pituitary development

SOX2 is expressed in the pituitary anlagen, Rathke’s Pouch (RP), from its induction at 9.0dpc. RP progenitors initially expand, later giving rise to all pituitary cell types. As cells differentiate, SOX2 expression is down-regulated, but a population of SOX2+ve cells persists until adulthood. These...

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Bibliographic Details
Main Author: Goldsmith, S.
Published: University College London (University of London) 2014
Subjects:
610
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.632096