The asymmetric synthesis of oxo-piperidines and oxo-pyrrolidines

Chapter 1 describes the attempts to synthesize piperidin-2-ones via an aza-Michael-Michael annulation, which were unsuccessful. A general route for the synthesis of piperidin-2,4-diones from β-keto esters via a Dieckmann cyclisation was proposed and five piperidin-2,4-diones with different substitue...

Full description

Bibliographic Details
Main Author: Yau, K. C.
Published: University College London (University of London) 2014
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631985