Flavin-containing monooxygenase 3 (FM03) : evolution, protein structure and causative mutations of Trimethylaminuria

Flavin-containing monooxygenase 3 (FM03) is a hepatic, microsomal enzyme important in the Phase I metabolism of xenobiotics. Numerous single nucleotide polymorphisms (SNPs) in FM03 have been identified and shown to affect the catalytic activity of the enzyme, with some destroying the activity altoge...

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Bibliographic Details
Main Author: Allerston, C. K. J.
Published: University College London (University of London) 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631816