Tools for next-generation transcriptional control in Chinese hamster ovary cell factories

Recombinant gene transcription in Chinese hamster ovary (CHO) cells, the dominant cell factory utilised for biopharmaceutical production, is still routinely regulated with a limited set of functionally ill-defined and uncontrollable genetic elements. This study presents novel transcription control t...

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Bibliographic Details
Main Author: Brown, Adam
Other Authors: James, David
Published: University of Sheffield 2014
Subjects:
660
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631433