A study of the effects of Ki-Ras inhibition by antisense deoxyoligonucleotides in a rat model of renal fibrosis
Ras monomeric GTPases are key molecules in the signalling pathway of renal fibrogenesis and exist in three isoforms (Kirsten, Harvey and Neural). The aim of this thesis was to determine whether inhibition of Ki-Ras expression by ASOs could ameliorate the process of renal fibrosis. All isoforms of Ra...
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King's College London (University of London)
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.631288 |