A study of the interaction between botulinum neurotoxin and cellular membranes

Eight genetically distinct serotypes (A-H) of Botulinum neurotoxin (BoNT) cause flaccid muscular paralysis through inhibition of neurotransmission at cholinergic nerve terminals. BoNT binds with specificity to the neuromuscular junction and enters through endocytosis. It translocates its catalytic m...

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Bibliographic Details
Main Author: Harris, Iain John
Other Authors: Acharya, K-Ravi
Published: University of Bath 2014
Subjects:
572
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.629651