The interaction of antimicrobial peptides with lipopolysaccharide aggregates and model membranes

Lipopolysaccharides (LPS) released from the outer membrane (OM) of Gram negative bacteria form aggregates which trigger an in ammatory response in humans and can result in severe septic shock. LPS molecules are heterogenic, macroamphiphilic oligosaccharides with a pro-in ammatory activity strictly r...

Full description

Bibliographic Details
Main Author: Bello, Gianluca
Published: King's College London (University of London) 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628439