Astrocyte-neuron interactions in the juvenile form of Batten Disease
The neuronal ceroid lipofuscinosis (NCLs, Batten Disease) are inherited, fatal neurodegenerative disorders of childhood. In all forms of NCL, astrocyte activation occurs early in the disease and precedes neuronal loss. However, in the most common juvenile form (JNCL), which is caused by a mutation i...
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King's College London (University of London)
2013
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628386 |