Astrocyte-neuron interactions in the juvenile form of Batten Disease

The neuronal ceroid lipofuscinosis (NCLs, Batten Disease) are inherited, fatal neurodegenerative disorders of childhood. In all forms of NCL, astrocyte activation occurs early in the disease and precedes neuronal loss. However, in the most common juvenile form (JNCL), which is caused by a mutation i...

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Bibliographic Details
Main Author: Parviainen, Lotta
Published: King's College London (University of London) 2013
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628386