Role of Rap and Rho GTPases in T-acute lymphoblastic leukaemia cell adhesion and migration
T-acute lymphoblastic leukaemia (T-ALL) is a common childhood cancer. Multiple genetic mutations have been identified in T-ALL patients. The most common is the mutation of the NOTCH 1 oncogene occurring in more than 50% of patients. Poor prognosis has often been shown to correlate with the migration...
Main Author: | |
---|---|
Published: |
King's College London (University of London)
2013
|
Subjects: | |
Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628331 |