X-Box Binding Protein-1 is important in maintenance of endothelial integrity and migration
Background - Sustained activation of spliced x-box binding protein-1 (XBP1), an endoplasmic reticulum stress response transcription factor, results in the development of atherosclerosis in apoE -/- mice. Histone deacetylases (HDACs) play a crucial role in transcriptional regulation through modulatio...
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King's College London (University of London)
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628201 |