A molecular genetic analysis of Crohn's disease susceptibility loci in psoriasis

Psoriasis is an immune-mediated skin disorder that is inherited as a complex trait. Genome-wide linkage and association studies have identified a major disease susceptibility locus (PSORS1) and several genetic determinants of smaller effect. At least two of these (the IL12B and IL23R genes) have ind...

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Bibliographic Details
Main Author: Quaranta, Maria
Published: King's College London (University of London) 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.628096