Mechanistic studies of small-molecule CFTR modulators
The cystic fibrosis transmembrane conductance regulator (CFTR) is a CI channel found in the apical membrane of epithelial cells. CFTR activity is tightly controlled by complex regulation. However, CFTR overactivity or loss-of-function mutations in CFTR are both disease causing conditions. The aims o...
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University of Bristol
2012
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.627986 |