Notch signalling dynamics during sprouting angiogenesis

During sprouting angiogenesis endothelial tip and stalk cells specification is regulated by a lateral-inhibition system involving Dll4/Notch and Vegf signalling pathways, the Vegf-Dll4/Notch negative feedback loop. Experimental observations and computational modelling have recently illustrated how t...

Full description

Bibliographic Details
Main Author: Ubezio, B.
Other Authors: Gerhardt, H.
Published: University College London (University of London) 2014
Subjects:
570
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626814