An investigation of the role of the P2X7 purinoceptor in the pathogenesis of diabetic nephropathy
P2X7 is a member of the P2X purinoceptor family and functions as an ATP-gated non-selective cation channel. Expression is greatest in cells of the immune system where it plays a key role in the orchestration of IL1β maturation and release. Diabetic nephropathy (DN) is traditionally considered a ‘met...
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University College London (University of London)
2014
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| Online Access: | https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626692 |