Biochemical characterisation of pre-replicative complex architecture
Pre-replicative complexes (pre-RCs), containing the helicase Mcm2-7, are assembled on origins of replication during G1 phase of the cell cycle. This ‘licenses’ origins for subsequent activation during S-phase. The loading of the Mcm2-7 complex requires ATP hydrolysis and the licensing factors ORC, C...
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University College London (University of London)
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626679 |