The role of multiple cell types in the development of regulatory T-cells
FoxP3 expressing regulatory T-cells (Treg) are essential for preventing autoimmunity by the immune system. The dynamics and signalling requirements for Treg development in the thymus are not well understood but are thought to integrate TCR, co-stimulatory and cytokine signalling. Previous studies ha...
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University College London (University of London)
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626483 |