Functional analysis of Hectd2 : a prion disease modifier associated with incubation time

Prion diseases in mice are characterised by prolonged, clinically silent incubation periods that are distinct in duration and reproducible. Incubation times are influenced by a number of factors with the major genetic determinant being variation within the prion protein gene, Prnp, however, differen...

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Bibliographic Details
Main Author: Begum, R.
Published: University College London (University of London) 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626403