Regulatory mechanisms of antigen encounter and BCR signalling

Activation of B cells is dependent on two events: the encounter of cognate antigen and the triggering of an adequate B cell receptor (BCR) signal. In vivo B cells encounter antigen within secondary lymphoid organs, such as lymph nodes (LNs). Here, specialised CD169+ macrophages, strategically locate...

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Bibliographic Details
Main Author: Castello, A.
Published: University College London (University of London) 2013
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626364