Fluorine-18 labelling of novel voltage-gated sodium channel ligands for applications in positron emission tomography (PET) imaging and oncology

Voltage-gated sodium channels (VGSCs) are essential for the initiation and propagation of neuronal impulses. Specifically, these channels initiate the rising phase of action potentials in electrically excitable cells, allowing the conduction of electrical information. There are 9 different sub-types...

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Bibliographic Details
Main Author: Desmond, A. L.
Published: University College London (University of London) 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626258