Replication stress links structural and numerical chromosomal instability in colorectal cancer

Replication stress links structural and numerical chromosomal instability in colorectal cancer

Chromosomal instability (CIN), describing an increased rate of numerical and structural chromosome aberrations, is a principal driver of inter-cellular genetic heterogeneity in tumours. CIN is widely observed in solid malignancies, and is associated with poor patient outcome and drug resistance. Des...

Full description

Bibliographic Details
Main Author:	Burrell, R. A.
Published:	University College London (University of London) 2013
Subjects:	570
Online Access:	http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.626067

Similar Items

An investigation of chromosomal instability survival mechanisms in cancer
by: Lee, A. J. X.
Published: (2012)

Chromosomal instability in near-diploid colorectal cancer: a link between numbers and structure.
by: Martine Muleris, et al.
Published: (2008-01-01)

APC and chromosome instability in colorectal cancer
by: C. M. Cabrera, et al.

DNA Replication Stress and Chromosomal Instability: Dangerous Liaisons
by: Therese Wilhelm, et al.
Published: (2020-06-01)

The role of brachyury in colorectal cancer cells
by: Jezkova, Jana
Published: (2015)

Beta-catenin complexes in colorectal cancer
by: Mackay, Craig Donald
Published: (2015)

Characterizing Microsatellite Instability and Chromosome Instability in Interval Colorectal Cancers
by: Amy L. Cisyk, et al.
Published: (2018-09-01)

Underpinning replication of protein-bound DNA by the accessory replicative helicase Rep
by: Brüning, Jan-Gert
Published: (2015)

The search for genetic variants that influence the risk of colorectal cancer
by: West, S. L.
Published: (2011)

A Role For Microtubule Dynamics For The Induction Of Chromosomal Instability And Cell Migration And Invasion In Human Cancer Cells
by: Berger, Katharina
Published: (2017)

Characterizing the Prevalence of Chromosome Instability in Interval Colorectal Cancer
by: A.L. Cisyk, et al.
Published: (2015-03-01)

Biochemical characterisation of pre-replicative complex architecture
by: Mehanna, A.
Published: (2014)

Structural and biochemical analysis of protein/RNA interactions during the initiation of dengue virus genome replication
by: Branfield, Lauren Elizabeth
Published: (2018)

PcrA function in plasmid replication
by: Chisty, L. T.
Published: (2014)

Knots and crosses : the roles of RNA structure and the 3B protein in foot-and-mouth disease virus replication
by: Ward, Joseph Charles James
Published: (2018)

Characterizing the prevalence of chromosomal instability in interval colorectal cancer
by: Cisyk, Amy L.
Published: (2014)

The role of chromosomal instability in therapy response of colorectal cancer
by: Liu, Xiyang
Published: (2017)

Hybridization in situ of genomic clones to barley chromosomes
by: Clark, Melody Susan
Published: (1988)

The role of the X chromosome in embryonic and postnatal growth
by: Snell, Daniel Mark
Published: (2018)

Preventive effects of fatty acids and phytochemicals in ApcMin/+ mouse, a model of colorectal cancer
by: Matos Lima, Jucineide
Published: (2010)

Characterisation of the Helix pomatia agglutinin binding glycoproteins of colorectal cancer cell lines and tissue samples
by: Saint-Guirons, Julien
Published: (2007)

Replication of the linear plasmids of Kluyveromyces lactis : analysis of the putative DNA polymerases
by: Ambrose, Charles A.
Published: (1993)

The role of protein kinases in DNA replication in Saccharomyces cerevisiae
by: Sweet, S.
Published: (2010)

Coronavirus proteins and their directed evolution to inhibit virus replication
by: Abdulsattar, Ban Oday
Published: (2017)

Chromosomal instability in BRAF mutant, microsatellite stable colorectal cancers.
by: Catherine E Bond, et al.
Published: (2012-01-01)

Characterization of chromosomal instability in murine colitis-associated colorectal cancer.
by: Marco Gerling, et al.
Published: (2011-01-01)

Mechanisms and functions of molecular interactions during plasmid rolling circle replication
by: Arbore, C.
Published: (2013)

Establishment of sister chromatid cohesion during DNA replication in Saccharomyces cerevisiae
by: Borges, V. S. F.
Published: (2012)

Creating site-specific abasic sites in the genome of Saccharomyces cerevisiae to analyse replication-associated lesion bypass
by: Colby, E. R.
Published: (2014)

Distinct Patterns of Structural and Numerical Chromosomal Instability Characterize Sporadic Ovarian Cancer
by: Jane Bayani, et al.
Published: (2008-10-01)

A functional study of the Y chromosome in the malaria vector Anopheles gambiae
by: Bernardini, Federica
Published: (2015)

A comparison of numerical and electrophoretic studies of the Enterobacteriaceae
by: Feltham, R. K. A.
Published: (1975)

A study of Raman spectroscopy as a clinical diagnostic tool for the detection of lynch syndrome/hereditary nonpolyposis colorectal cancer (HNPCC)
by: Gaifulina, Riana
Published: (2017)

A Mitotic Actin Regulating Pathway Induces Chromosomal Instability In Human Cancer Cells
by: Glaubke, Elina
Published: (2020)

Studies on the replication of rhinovirus RNA
by: Koliais, Stefanos I.
Published: (1973)

Aurora-A Expression Is Independently Associated with Chromosomal Instability in Colorectal Cancer
by: Yoshifumi Baba, et al.
Published: (2009-05-01)

Proteogenomic Characterization of Ovarian HGSC Implicates Mitotic Kinases, Replication Stress in Observed Chromosomal Instability
by: Jason E. McDermott, et al.
Published: (2020-08-01)

Proteogenomic Characterization of Ovarian HGSC Implicates Mitotic Kinases, Replication Stress in Observed Chromosomal Instability
by: Jason E. McDermott, et al.
Published: (2020-04-01)

Understanding DELLA in wheat : linking genotype to phenotype
by: Saville, Robert Jack
Published: (2011)

Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer
by: Ganjei-Azar Parvin, et al.
Published: (2011-03-01)

Cannot write session to /tmp/vufind_sessions/sess_je0gkhbp37c3tiolh0oa246ugt