The innate immune response to viruses : a look into cytosolic nucleic acid sensing

Upon infection with a virus, a cellular innate immune response is rapidly initiated to contain the pathogen. A potent interferon (IFN)-α/β cytokine response underlies host defence by prompting the expression of antiviral genes and stimulating adaptive immunity. Pattern recognition receptors (PRRs) a...

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Bibliographic Details
Main Author: Goubau, D.
Published: University College London (University of London) 2012
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625980