An evaluation of bioprocess development approaches for the precipitation-based purification of IgG monoclonal antibodies

This thesis investigates bioprocess development approaches for the precipitation-based purification of IgG monoclonal antibodies (mAb) from clarified cell culture supernatant. A high throughput platform using microgram quantities of IgG was developed for the rapid identification and selection of sui...

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Bibliographic Details
Main Author: Knevelman, C. A.
Published: University College London (University of London) 2011
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625688