CCL6 is a negative regulator of myelopoiesis and phagocyte responses : characterisation of CCL6 deficiency in mice

Chemokines play a fundamental role in regulating phagocyte responses during an infection. To test a role of the unusual β chemokine CCL6 in vivo, a mouse model was generated through germline mutagenesis of CCL6. Increased number of bone-marrow cells, myelopoietic activity and enhanced phagocyte recr...

Full description

Bibliographic Details
Main Author: Mahbub, S.
Published: University College London (University of London) 2009
Subjects:
616
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625204