Cellular mechanisms in prion-mediated neurodegeneration
Prion diseases are fatal neurodegenerative disorders of both humans and other animals. The cause of prion-mediated neurodegeneration by conversion of the normal cellular prion protein (PrPC) to the disease-related isoform (PrPSc) remains unknown. Increasing evidence suggests a role for the ubiquitin...
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University College London (University of London)
2009
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625154 |