The cellular machinery that underpins recycling through the Trans-Golgi Network
Retromer is a pentameric complex required for endosome to TGN transport of transmembrane cargo, such that in mammalian cells a lack of retromer function leads to a mannose-6-phosphate receptor defect in the delivery of hydrolases to lysosomes. CLN3 is a multipass membrane protein that is localised t...
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University College London (University of London)
2009
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.625152 |