Lithiation/trapping of N-Boc piperazines and synthesis of the (–)-sparteine surrogate
This thesis describes some novel aspects of the s-BuLi mediated lithiation/trapping of N-Boc heterocycles, including a systematic investigation into the lithiation/trapping of N-Boc piperazines. Chapter 2 details an in situ ReactIR™ investigation into the time required for both the lithiation and tr...
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University of York
2014
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.624608 |