Matrix disruption and altered cell phenotypes in degenerated intervertebral discs

Chronic back pain is associated with specific pathological changes in intervertebral discs, including fissuring of the annulus fibrosus, defects in the vertebral body endplates, and disc herniation. The greatest risk factors for disc pathology are age, spinal level, and genetic inheritance, and majo...

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Bibliographic Details
Main Author: Lama, Polly
Published: University of Bristol 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618549