The role of age-related DNA methylation in the development of age-related disease
Alterations in DNA methylation can have dramatic effects on gene transcription, and in particular, hypermethylation of promoter associated CpG islands is known to lead to gene inactivation. Altered patterns of DNA methylation play a key role in the development of cancer and may also play important r...
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University of Newcastle upon Tyne
2013
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.618208 |