Structural aspects of talin regulation through Rap1A signalling
At the nascent focal adhesion, GTPase Rap1A recruits the adaptor protein RIAM (Rap1 Interacting Adaptor Molecule), and RIAM recruits the scaffold protein talin facilitating integrin activation (Lee et al., 2009). As the nascent adhesion matures, actin linkages are strengthened via recruitment of the...
| Main Author: | |
|---|---|
| Other Authors: | |
| Published: |
University of Liverpool
2013
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.617408 |