Genetic interactions of the Saccharomyces cerevisiae DNA Repair Factor PSO2

DNA interstrand cross-links (ICLs) present a major challenge to cells, covalently binding the two DNA strands together and preventing fundamental cellular processes, such as transcription and replication. Failure to repair such les ions can lead to the formation of DNA double-strand breaks (DSBs), g...

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Bibliographic Details
Main Author: Ward, Thomas Anthony
Published: Oxford Brookes University 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.616316