Synthesis and biological activity of some specialised minor groove binders
Minor groove binders (MGBs) are molecules which bind selectively to the minor groove of DNA. Distamycin 1 and netropsin 2 are naturally occurring MOBs, and are members of the polypyrrole class of compounds. These compounds consist of two and three methylpyrrole monomers linked by ami des, with a hea...
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University of Strathclyde
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.607438 |