Brain-selective kinase (BRSK) interactions with tau as a cause of neurodegeneration

Tauopathies are a group of neurodegenerative diseases associated with the build-up of intracellular aggregates of the microtubule-associated protein (MAP) tau, called neurofibrillary tangles (NFT). The tau found in NFTs is known to be highly phosphorylated, and as such a number of tau kinases have b...

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Bibliographic Details
Main Author: Cameron, Charles S.
Published: University of Warwick 2013
Subjects:
570
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.606109