'High' temperature asymmetric lithiation of N-Boc heterocycles : synthesis of tetra-substituted pyrrolidines

This thesis describes the study of new methodologies for the asymmetric synthesis of N-Boc heterocycles using lithiation chemistry, with the main focus on N-Boc pyrrolidine. The “high” temperature asymmetric lithiation-trapping of five-membered heterocycles N-Boc pyrrolidine and N-Boc imidazolidine...

Full description

Bibliographic Details
Main Author: Gelardi, Giacomo
Other Authors: O'Brien, Peter
Published: University of York 2014
Subjects:
540
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.605472