An investigation into the role of remyelination failure as a contributing cause of axonal degeneration in the CNS

Chapter 1 of the thesis reviews axonal degeneration in MS and the several mechanisms thought to contribute to axonal degeneration therein. Analyses of models of primary demyelination indicated that cuprizone intoxication combined with 40 Grays of X-irradiation to inhibit remyelination would provide...

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Bibliographic Details
Main Author: Irvine, K. A.
Published: University of Cambridge 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604950