Studies towards the total synthesis of neolaulimalide and laulimalide and synthesis of novel laulimalide analogues
Neolaulimalide (1) and laulimalide (2) are structurally related cytotoxic marine polyketides belonging to the microtubule-stabilising family of anti-cancer agents. Our approach toward the laulimalides is based on the highly convergent synthesis of a common advanced intermediate 3 which, it was imagi...
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University of Cambridge
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604858 |