Mechanisms regulating the imprinted tumour suppressor gene DIRAS3 in normal development and cancer
In this thesis I have extended previous work on DNA methylation of <i>DIRAS3 </i>using quantitative methods and studied a broad range of tissues. This leads to identification of a probable germline DMR. I have identified CTCF and cohesion binding sites in the <i>DIRAS3</i> lo...
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University of Cambridge
2010
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604715 |