Studies towards the total synthesis of the spongistatins

The spongistatins are a novel class of recently isolated marine macrolides exhibiting potent activity against a series of cancer cell lines, through inhibition of microtubule assembly. Progress towards the total synthesis of the spongistatins is described. In particular, the stereocontrolled synthes...

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Bibliographic Details
Main Author: Hodgson, A.
Published: University of Cambridge 2001
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.604132