Regulation of cohesin and Plk1 function in mouse oocytes

Faithful segregation of homologous chromosomes during the first meiotic division (MI) is essential for the formation of haploid gametes. Recent research in our lab and others has shown that female ageing is associated with depletion of chromosomal cohesin and is accompanied by a marked decline in th...

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Bibliographic Details
Main Author: Kalleas, Dimitrios
Published: University of Newcastle upon Tyne 2013
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603364