Structural chemistry and structural biology of anti-cancer agents binding to proteins with reference to a model protein and to heparanase

The binding of cisplatin and carboplatin to hen egg white lysozyme, a model protein, has been studied using X-ray crystallography under many different crystallisation conditions (Tanley et al, 2012a; 2012b; 2013a; 2013b and Helliwell & Tanley, 2013). From this work, many new results have been ob...

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Bibliographic Details
Main Author: Tanley, Simon
Other Authors: Helliwell, John
Published: University of Manchester 2014
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.603264