Selective interactions of nuclear receptors and cofactors: novel targets for drug discovery

Nuclear receptors (NRs) are biomedically important transcription factors that regulate gene expression by recruitment of coactivators and corepressors (cofactors) to target gene promoters. Humans express 48 different NRs.and their isoforms, approximately half of which are orphans that have no recogn...

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Bibliographic Details
Main Author: Fulton, Joel
Published: University of Nottingham 2012
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.602958